CompBio Bridge logo, Fractional Strategy and Management

Do you need to close the divide between data science and the wet lab? Or do you need to connect your startup vision to actual implementation?

At CompBio Bridge, we help biotech companies navigate the complex world of computational biology, bioinformatics, and research informatics. Offering flexible fractional leadership and deep expertise, we provide the strategic support needed to drive discovery and maximize the impact of your data.

Whether you're scaling research efforts or refining your strategy, CompBio Bridge is your partner in bridging the gap between science and success.

Our Services

Strategy

We provide expert guidance in creating strategic roadmaps for biotech organizations, aligning scientific innovation with business goals. We will help you to identify opportunities and mitigate risks so that your R&D programs are both cutting-edge and commercially viable.

Management

With extensive experience leading cross-functional teams, we ensure your projects remain on track and achieve impactful results. Our multidisciplinary scientific expertise fosters seamless collaboration, streamlines communication, and refines processes to drive productivity and spark innovation.

Staffing/Hiring

Computational biologists, bioinformaticians, data scientists, ML engineers – who do you need? We specialize in building your team with the right people for you, as well as providing guidance and mentoring for staff growth and performance. Our expertise ensures your workforce meets technical needs and drives success.

Technical Areas of Expertise

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Computational Biology

We are seasoned experts in computational biology, leveraging advanced data analysis and machine learning to solve complex biological problems. We have developed computational pipelines and algorithms for target identification, biomarker discovery, and therapeutic advancements, ensuring data-driven solutions that are biologically grounded.

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Functional Genomics

With deep expertise in functional genomics, we have applied cutting-edge techniques like RNA sequencing, proteomics, and genetic screening to uncover mechanisms of disease and therapeutic targets. Our ability to integrate multi-omic data provides valuable insights that accelerate discovery and development.

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Research Informatics

We excel in research informatics, designing and implementing systems for data management and analysis. From LIMS and ELN systems to automation and high-throughput workflows, we ensure research processes are efficient, scalable, and optimized for scientific success. We have experience with many systems, including Benchling, Dotmatics, Arxspan, Core LIMS, Labguru and more.

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Christopher B. Yohn, Ph.D., Principal

Chris is a biotechnology leader with over 30 years of experience blending computational biology, bioinformatics and wet lab expertise. His career includes impactful roles at companies such as TRexBio, UNITY Biotechnology and Sapphire Energy, where he contributed to advancements in areas as diverse as immune system modulation, aging biology, algae biofuels and personalized cancer vaccines. With a foundation in molecular biology and genetics, Dr. Yohn has applied his skills to areas including target discovery/validation, platform development and translational research, complementing his computational expertise in data analysis, machine learning and bioinformatics.

From discovering biomarkers and optimizing therapeutic strategies to leading cross-functional teams and managing multimillion-dollar research programs, Dr. Yohn brings a unique ability to translate complex science into actionable insights. He earned his Ph.D. in Macromolecular and Cellular Structure and Chemistry from The Scripps Research Institute and a B.S in Biomedical Engineering from Northwestern University.

Why choose us?

CompBio Bridge provides unparalleled expertise at the intersection of biology and data science, backed by over three decades of experience in biotech innovation.

We have a proven track record of solving complex challenges, from developing cutting-edge bioinformatics platforms to leading multimillion-dollar research programs. Our unique combination of computational and wet lab expertise enables us to approach problems holistically, ensuring robust, data-driven solutions that are biologically grounded. With extensive leadership experience, we excel in mentoring high-performing teams, driving strategic initiatives, and delivering results that accelerate discovery and development.

Whether you need to refine your R&D strategy, uncover actionable insights from large datasets, or implement innovative technologies, CompBio Bridge is the partner you can trust to move your projects forward efficiently and effectively.

Companies we've worked with

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